Jesus said, “Come to Me, all you who are weary and burdened, and I will give you rest. Take My yoke upon you, and learn from Me, because I am gentle and humble in heart, and you will find rest for your souls. For My yoke is easy, and My burden is light” (Matthew 11:28-30). Like John the Baptist, we must say to depressed people, “Here is the Lamb of God!” (John 1:29).

Many Christians will overcome depression when they truly grasp some foundational truths:

Realization of the hope we have in God. He encourages us to “call upon [Him] in the day of trouble; I will deliver you” (Psalm 50:15). Hopelessness is one of the hallmark symptoms of depression. The grace of God in Jesus Christ is the sum of all hope (Colossians 1:5-6, 23, 27; 1 Timothy 1:1). Paul, a man who had more than his share of tribulation and suffering, proclaimed, “We have placed our hope in Him that He will deliver us again” (2 Corinthians 1:10).

Restoration of the joy of salvation. We live in a fallen world, one in which good things may come to an end. The tragic dimension of life will be present until the kingdom of God comes fully in Jesus’ return. The joy of salvation comes from realizing, again and again, that our sins have been forgiven and that we will live forever with the eternally happy God, who desires that we share in His joy.

Active love for God and others. Love for God and others is essential because depressed people often find themselves sucked into a vortex of morbid self-involvement, which keeps them from following the great commandments given by the Great Physician, the medicine that many depressed people need above all else (Matthew 22:36-40). When depressed people begin to love God with all their heart, soul, mind and strength and demonstrate love for and to others, their depression often begins to evaporate.